FOA Title: 
Grant Type: 
Primary IC: 
Release Date: 
Oct 15 2018
Expiration Date: 
AC Source: 
REQUEST PROPOSAL RFP): BIOINFORMATICS RESOURCE CENTERS INFECTIOUS DISEASES, RFP-NIAID-DMID-NIHAI201800005 Notice Number: NOT-AI-19-009 Key Dates Release Date:October 15, 2018 Related Announcements None Issued National Institute Allergy Infectious Diseases NIAID) Purpose National Institute Allergy Infectious Diseases NIAID), National Institutes Health NIH), the Department Health Human Services DHHS) supports research related the basic understanding microbiology immunology leading the development vaccines, therapeutics, medical diagnostics the prevention, treatment, diagnosis infectious immune-mediated diseases.   NIAID, Division Microbiology Infectious Diseases DMID) a requirement maintain Bioinformatics Resource Centers BRCs), have become critical resource data tools generated NIAID supported programs other publicly accessible data the infectious disease research community.   NIAID made significant investment funding basic clinical research projects are generating large, diverse complex data sets including genomics/omics data, clinical data, immune phenotyping assay data, imaging other data sets. infectious diseases immune mediated diseases communities become data-intense enterprise a priority NIAID to transform data knowledge understand pathogenesis, transmission, evolution the pathogen, pathogen-host interactions the host response infectious diseases inform development new improved diagnostics, therapeutics, vaccines. NIAID invested bioinformatics data science data generated NIAID intramural extramural communities has expanded activities data management systems, bioinformatics resource centers data repositories/knowledgebases have provided broad scientific community user friendly access open data analytical tools.   Since inception 2004, NIAID’s BRCs focused supporting providing genome sequence databases annotation microbial organisms. BRCs provided infectious disease research community publicly accessible systems store, update, integrate display genome sequence data its annotation, functional genomics other ldquo;omics” data, other associated data information a large variety human pathogens vectors human pathogens related microbial species strains. BRC systems allow users query analyze data. a result, BRCs become public repository primary resource data tools generated NIAID supported programs other publicly accessible data the infectious disease research community.   objective this solicitation to continue support the BRCs provide data-driven, production-level sustainable computational platform(s) enable sharing access usable re-usable data, portable computational tools standards support interoperability the infectious diseases research community. Through effort NIAID continue provide bioinformatics services training support large-scale, system level diverse data integration modeling, enable predictive biology pathogens host-pathogen interactions will accelerate discovery research, clinical investigation, therapeutic development infectious diseases. addition, platform infrastructure expected serve a model future NIAID systems. change the previous competition should noted: to 2) BRCs be awarded one 1) contract awarded bacterial species viral families one 1) contract awarded protozoan species, fungi invertebrate vectors human pathogens. Offerors propose one both data resources the group organisms. Funding under prior solicitation NOT required submission this solicitation.   is anticipated two 2) cost-reimbursement plus fixed-fee, level-of-effort, type contracts be awarded a one-year base period performance beginning or around September 1, 2019. Awards expected include four 4) one-year option periods. total period performance, including options, five 5) years. Government’s base level-of-effort requirement estimated 43,680 direct labor hours each contract period, equating 21 Full Time Equivalents FTEs) an FTE being defined 2,080 direct labor hours. addition the base level-of-effort, contract period shall contain option quantity up nine 9) additional FTEs.   NIAID recognizes a single organization institution not the full spectrum expertise facilities required perform activities set forth the Statement Work. Contractors need be supported a certain extent the expertise resources other organizations persons through consortia agreements, partnerships, subcontracts, and/or consultants. However, contractors shall responsible ALL work performed shall responsible project planning, initiation, implementation, management communication; evaluation, selection, management subcontractors; for deliverables specified this contract.   Any responsible Offeror submit proposal will considered the Agency. Request Proposal RFP) available electronically may accessed through FedBizOpps  notice does commit Government award contract. collect calls be accepted. facsimile transmissions be accepted   this solicitation, NIAID requires proposals be submitted via 2) methods: 1) Disc CD DVD) 2) Online via NIAID electronic Contract Proposal Submission eCPS) website. content the disc online proposals must identical. Submission proposals facsimile e-mail not acceptable.   directions using eCPS, to website and click ldquo;How Submit.” Inquiries Please direct inquiries to: Primary Contact: Brian Madgey National Institute Allergy Infectious Diseases NIAID) Telephone: 240-627-3712 Email:   Secondary Contact: Stanley Knight National Institute Allergy Infectious Diseases NIAID) Telephone: 240-669-5181 Email: