Development of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndromE) Project Data Coordinating Center (U2C Clinical Trial Not Allowed)
Dec 13 2019
Feb 15 2020
The objective of this FOA is to support the development of the Data Coordinating Center for the NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) project, which consists of the following components: a Data Portal Core, a Data Management Core, and an Administrative and Outreach Core. The goal of the web-based Data Portal is to accelerate discovery of etiology and biologic pathways underlying the comorbidities of Down syndrome by facilitating access to and querying of data from cohorts of individuals with Down syndrome. The Data Portal will facilitate access to aggregated and harmonized data to empower analyses among the Down syndrome research community, as well as the broader scientific community. The Data Management Core will work with INCLUDE investigators and other data generators to facilitate data collection, processing, and harmonization. The Administrative and Outreach Core will oversee administrative activities, work closely with a Steering Committee and INCLUDE program staff, and provide outreach and education to the research community on using the Data Portal.