FOA Title: 
Notice of Intent to Publish a Funding Opportunity Announcement for Pediatric Research using Integrated Sensor Monitoring Systems (PRISMS): Data and Software Coordination and Integration Center (DSCIC) (U24)
Grant Type: 
Primary IC: 
Release Date: 
Feb 19 2015
Expiration Date: 
AC Source: 
Notice Intent Publish Funding Opportunity Announcement Pediatric Research using Integrated Sensor Monitoring Systems PRISMS): Data Software Coordination Integration Center Asthma DSCIC) U24) Notice Number: NOT-EB-15-006 Key Dates Release Date: February 19, 2015 Estimated Publication Date Announcement: March 2015  First Estimated Application Due Date: 2015  Earliest Estimated Award Date: September 2015  Earliest Estimated Start Date: September 2015  Related Announcements RFA-EB-15-004 NOT-EB-15-004 NOT-EB-15-005 Issued National Institute Biomedical Imaging Bioengineering NIBIB) Purpose National Institute Biomedical Imaging Bioengineering NIBIB) intends promote new Program publishing three Funding Opportunity Announcements FOA) solicit applications research the development sensor-based health monitoring systems pediatric asthma. Accumulating evidence pointing toward exposures the modern environment contributors the etiology severity many pediatric health care problems such asthma, cancer, childhood obesity coupled Type 2 diabetes. Despite recent gains knowledge environmental contributions the causation chronic disease children, major questions the impact the environment children's health remain unanswered due lack exposure metrics.  Asthma a common condition childhood currently affecting approximately 7 million children the United States 9.3% the pediatric population. is chronic condition characterized inflammation the lower respiratory track airways prone acute exacerbations secondary a variety triggers including, not limited to, infections, pollens, smoke, mold, chemicals, etc. Encouragingly, mortality rates secondary asthma appear be decreasing, however morbidity children remains substantial. Data suggest asthma the third most common cause hospitalization children less 15 years. is leading cause school absenteeism more 14 million lost school days children had asthma exacerbation the previous year. Significant disparities exist among children asthma. example, racial ethnic disparities exist African American Puerto Rican children incurring disproportionate part the burden. Moreover, children lower socioeconomic conditions also tend be disproportionately affected. a recent report, prevalence rate asthma among children whose health status described fair poor 37% compared only 15% among those defined being good health 7.5% those a very good excellent health status Recent technological advances wearable non-wearable sensors, microelectronics integration miniaturization, low-power electronics, wireless networking, mobile computing, cloud computing offer new ways collect interpret data environments, behaviors, physiology, health.  development use an array sensors collect real life environmental physiological data among pediatric patients enable rigorous testing many hypotheses environmentally-related chronic pediatric illnesses such asthma. Sensors be coupled wireless communications, data treatment algorithms, visualization tools, a robust integrated health monitoring system. work required develop health monitoring systems study pediatric asthma be accomplished using three related FOAs create Pediatric Research using Integrated Sensor Monitoring Systems PRISMS) Program. FOA NOT-EB-15-005) fund U54 Centers create new informatics platforms will support smart phones collect data multiple sensors, analyze data, present data the user age appropriate ways, compile personalized health status information, securely upload data over Internet a data center. second FOA notice, NOT-EB-15-006) support Data Software Coordination Integration Center U24) will coordinate integrate outputs the PRISMS Program. third FOA NOT-EB-15-004) fund development arrays wearable non-wearable wireless sensors, monitoring users’ environmental conditions, physiological signals, activity behavior that plug play", physically wirelessly, the informatics platform NOT-EB-15-005). three arms the PRISMS Program be expected work very closely together ensure functionality the systems a unit, well the individual projects. Notice being provided allow potential applicants sufficient time develop meaningful collaborations responsive projects.  FOA expected be published March 2015 an expected application due date May 2015. FOA utilize U24 activity code. Details the planned FOA provided below. Research Initiative Details Notice to announce upcoming FOA will seek applications develop Data Software Coordination Integration Center DSCIC) will coordinate integrate outputs the U54 Informatics Platform Centers component the PRISMS Initiative.  goal the PRISMS initiative to develop integrated sensor-based health monitoring system will establish gain new insights environmental determinants asthma. NIH expects this DSCIC focus coordinating integrating data acquired environmental, physiological, behavioral pediatric exposure factors natural environments, well tools developed process data. successful DSCIC ensure consistent annotation data tools generated within PRISMS program, incorporate without replicating databases) relevant non-PRISMS data the PRISMS resource; support integration relevant data tools allow seamless exploration the PRISMS program’s output a broad range biomedical researchers; support linkages outside knowledge bases, data portals, resources; support training integrated sensor monitoring data science skills; build innovative access query tools disparate databases hosting multiple data types; disseminate resulting tools resources the broad range biomedical researchers. Notice encourages investigators expertise insights this area science, engineering, informatics, together clinical expertise pediatric asthma, begin consider applying this new FOA. APPLICATIONS NOT BEING SOLICITED THIS TIME. Inquiries Please direct inquiries to: Christine A. Kelley, Ph.D. National Institute Biomedical Imaging Bioengineering Telephone: 301-451-4778 Email:
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