FOA Title: 
Request for Information: Input to the National Eye Institute Strategic Plan: 2020 Vision for the Future
Grant Type: 
Primary IC: 
Release Date: 
Dec 04 2019
Expiration Date: 
AC Source: 
Request Information: Input the National Eye Institute Strategic Plan: 2020 Vision the Future Notice Number: NOT-EY-20-002 Key Dates Release Date: December 4, 2019 Response Date: January 08, 2020 Related Announcements None Issued National Eye Institute NEI) Purpose National Eye Institute NEI) establishing strategic plan, 2020 Vision the Future, under auspices the National Advisory Eye Council. developing content, NEI engage scientists, clinicians, patients, vision advocates, the public. Notice a time-sensitive Request Information RFI) solicit feedback research needs, opportunities, areas emphasis vision research over next five years. Background Last year, NEI celebrated 50th anniversary since being established Congress established 1968. NEI highlighted multitude scientific medical advances by NEI-supported researchers the impacts vision care. Charged protect preserve vision the American people, NEI continues support basic clinical research unravels mysteries how vision works a fundamental level provides patients new therapies standards care maintain improve quality life. NEI 50th Anniversary also provoked scientific, medical, patient communities reflect upon gaps opportunities vision research. NEI Strategic Plan seeks distill those reflections a cohesive document will guide efforts address those gaps opportunities over next five years. Ultimately, NEI stakeholders provide catalyst identifying implementing goals. that end, NEI welcomes feedback stakeholders the drafting the strategic plan. 21st Century Cures Act requires NIH institutes centers regularly update strategic plans. 2012, NEI released strategic plan, ldquo;Vision Research: Needs, Gaps, Opportunities”, organized around six core anatomically focused program areas Retinal Diseases; Corneal Diseases; Lens Cataract; Glaucoma Optic Neuropathies; Strabismus, Amblyopia, Visual Processing; Low Vision Blindness Rehabilitation). developing plan, NEI created panels scientists patient representatives each program. plan also sparked Audacious Goals Initiative AGI), sought broad-based community input identify ideas transform vision research care. NEI wants build some the ideas generated through AGI has proposed cross-cutting Areas Emphasis organize thinking the next NEI strategic plan. Information Requested NEI invites scientific research community, health professionals, patient advocates, professional societies, the general public provide input the following topics: most significant scientific discoveries vision research since 2012 New opportunities have enabled scientific discoveries technology development Needs gaps research, health, quality-of-life should addressed the NEI organize the planning process, NEI proposed following seven cross-cutting Areas Emphasis foster dialogues across traditional vision research disciplines to best capitalize recent scientific opportunities. NEI particularly interested input relating these areas emphasis. However, NEI always been—and continue be—committed high quality investigator-initiated research will fund best science across broad spectrum vision research. Areas Emphasis Visual System Health Disease Genes Disease Mechanisms—In past 13 years, vision scientists discovered genes through new genomic techniques such GWAS. emphasis is leverage those discoveries complete jigsaw puzzle disease pathways Biology Neuroscience Vision—Vision neuroscientists study retinal development, organization, optic nerve regrowth, brain processing, corneal pain. fields usually discussed isolation-NEI proposes emphasizing commonality visual neuroscience together Immune System Eye Health—While corneal ocular surface the front lines against outside environment, immune system been implicated AMD, glaucoma, cataract, Sjogren’s Disease, optic neuritis many ocular pathologies Capitalizing Emerging Fields Regenerative Medicine—NEI already leader stem cells regenerative medicine studies ongoing corneal limbal cells, AMD, the Audacious Goals Initiative developing imaging tools, searching regenerative factors, creating animal models both retina the optic nerve Data Science—Data science an emerging field has rapidly transformed almost areas vision research genomics imaging neuroscience. field includes data management, bioinformatics, analytics predictive modeling. are complicated issues such data sharing, ethics, methodologies, the topic also includes identifying promoting new applications vision research, especially basic clinical research incorporates artificial intelligence Preventing Vision Loss Enhancing Well-being Individual Quality Life—This area focuses the patient perspective encompasses blindness rehabilitation brain plasticity, assistive devices independent living, also depression patients coping vision loss Public Health Disparities Research—In contrast the Individual Quality Life, aspect public health focus population health, based partly recommendations the 2016 NASEM report Vision. topic covers epidemiology, health services research, women’s health minority health disparities research, the 21st Century Cures Act specifically enjoins NIH focus Responses Responses this RFI voluntary are meant information planning purposes only. Any information submitted response this RFI shall be construed a solicitation, grant application, cooperative agreement, obligation part the National Institutes Health NIH), Department Health Human Services HHS), the United States Federal Government. not include any proprietary, classified, sensitive information. Please respond January 8, 2020 using following form: Inquiries Please direct inquiries to: National Eye Institute NEI) Office Program Planning AnalysisEmail: 301-496-4308