Friday, December 12, 2025
Meredith C.B. Adams, MD, MS will present "Building the Future of Clinical Data: From Standardization to AI-Powered Federation" from 12:00 p.m.–1:00 p.m. EST.
About the Seminar
This presentation will examine how clinical researchers developed systematic data standardization, AI-powered automation, and federated architectures are transforming clinical research infrastructure. Drawing from leadership across multiple NIH HEAL Initiative networks, Dr. Adams will present a roadmap from evidence-based research tools (including the NIH HEAL MME Calculator) to real-world data standardization frameworks covering nearly half the US population through claims data integration, with resources to make them more accessible. The presentation will demonstrate how large language models are removing barriers for complex data operations, making sophisticated analyses accessible to non-technical researchers. This talk illustrates how architectural thinking, rather than incremental improvements, can fundamentally alter the economics and scalability of clinical data integration, offering a vision for global research collaboration that maintains both security and accessibility through standardized, automated clinical researcher friendly tools. The session will be of particular interest to data scientists, clinical researchers, and policy leaders working on data infrastructure challenges in biomedical research.
About the Speaker
Meredith C.B. Adams, MD, MS, FASA, FAMIA is Associate Professor of Anesthesiology, Artificial Intelligence, Translational Neuroscience, and Public Health Sciences at Wake Forest University School of Medicine and Chair of the NIH HEAL Data Ecosystem Collective Board. As Principal Investigator of multiple NIH HEAL Initiative programs (including MIRHIQL Resource Center, Wake Forest DISC, and IMPOWR IDEA-CC), she leads transformative data infrastructure development for chronic pain and opioid use disorder research. Dr. Adams serves as Secretary/Treasurer of the International Anesthesia Research Society and has received numerous honors including the 2024 NIH HEAL Golden Neuron Pain Rising Star Researcher Award and 2023 NIH HEAL Director's Trailblazer Award. Her innovative tools, including the NIH HEAL MME Calculator, CDE2OMOP mapping system, and Gen3-based federated data commons, have become essential infrastructure for clinical research networks. With expertise spanning clinical informatics, machine learning, and health policy, Dr. Adams bridges clinical domain knowledge with advanced computational methods to create research frameworks that enable access to sophisticated data analytics while maintaining rigorous scientific standards.
About the Seminar Series
The seminar is open to the public and registration is required each month. Individuals who need interpreting services and/or other reasonable accommodations to participate in this event should contact Allison Hurst at 301-670-4990. Requests should be made at least five days in advance of the event.
The National Institutes of Health (NIH) Office of Data Science Strategy hosts this seminar series to highlight examples of data sharing and reuse on the second Friday of each month at noon ET. The monthly series highlights researchers who have taken existing data and found clever ways to reuse the data or generate new findings. A different NIH institute or center will also share its data science activities each month.