NIH Awards 28 Supplements to Advance Software Tools for Open Science

Tuesday, December 29, 2020

In 2020 the National Institutes of Health (NIH) Office of Data Science Strategy (ODSS) and 24 institutes and centers (ICs) at NIH announced a notice for administrative supplements to enhance software tool development for open science (NOT-OD-20-073). Twenty-eight awards were made in the fall of 2020 to principal investigators at 26 different institutions across the United States.

These supplements will invest in research software tools with recognized value in a scientific community to enhance their impact by leveraging best practices in software development and advances in cloud computing. The supplements are intended to support collaborations between biomedical scientists and software engineers to enhance the design, implementation, and “cloud-readiness” of research software.

Through these awards, the NIH Office of Data Science Strategy and a trans-NIH team will help researchers who have developed scientifically valuable software to make tools sustainable, contribute to open science, and take advantage of new data science and computing paradigms.

Award Recipients
Principal InvestigatorInstitutionProject TitleNIH IC
Apkar Vania ApkarianNorthwestern University at ChicagoBrain Pathophysiology of Osteoarthritis PainNIAMS
Sylvain BouixBrigham and Women's HospitalHigh Resolution, Comprehensive Atlases of the Human Brain MorphologyNIMH
Gregory R BowmanWashington UniversityAllosteric impact of non-active-site mutations on enzymatic functionNIGMS
Laurel H. CarneyUniversity of RochesterAuditory Processing of Complex SoundsNIDCD
Brian Yuan ChenLehigh UniversityAlgorithmic identification of binding specificity mechanisms in proteinsNIGMS
Gerardo Andres CisnerosUniversity of North TexasInvestigation of DNA Modifying Enzymes by Computational Simulations: Development and ApplicationsNIGMS
Gaudenz DanuserUT Southwestern Medical CenterFunctional causality in regulating cell morphogenesisNIGMS
Shireen Youssef ElhabianUniversity of UtahAnatomy Directly from Imagery: General-purpose, Scalable, and Open-source Machine Learning ApproachesNIAMS
Melanie Fried-OkenOregon Health & Science UniversityClinic Interactions of a Brain-Computer Interface for CommunicationNIDCD
Ryan GutenkunstUniversity of ArizonaJoint inferences of natural selection between sites and populationsNIGMS
John H.L. HansenUniversity of Texas DallasCCI-Mobile: Signal Processing Advancements for Cochlear Implant Users in Naturalistic EnvironmentsNIDCD
Carl KesselmanUniversity of Southern CaliforniaUSC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration HubNIDCR
Steven H. KleinsteinYale UniversityComputational tools for the analysis of high-throughput immunoglobulin sequencing experimentsNIAID
Francine LadenHarvard School of Public HealthRelationship Between Multiple Environmental Exposures and CVD Incidence and Survival: Vulnerability and SusceptibilityNIEHS
Suzanne Margaret LealColumbia University Health SciencesInnovative approaches to elucidate the genetic etiology of age-related hearing impairment and tinnitusNIDCD
Yaling LiuLehigh UniversityMultiscale Predictive Modeling of Blood Cell Damage with Experimental VerificationNHLBI
Shaun Aengus MahonyPennsylvania State University-University ParkGenome-wide structural organization of proteins within human gene regulatory complexesNIGMS
Nadine MartinTemple University of the CommonwealthTranslation and Clinical Implementation of a Test of Language and Short-term Memory (STM) in AphasiaNIDCD
David P MillerWake Forest University Health SciencesEffectiveness and Implementation of mPATH-CRC:  A Mobile Health System for Colorectal Cancer ScreeningNCI
David Lowell MobleyUniversity of California-IrvineAdvancing predictive physical modeling through focused development of model systems to drive new modeling innovationsNIGMS
Matteo PellegriniUniversity of California Los AngelesEnhancing the International Molecular Exchange (IMEx): Providing an Improved Community-Oriented Molecular Interactions ResourceNIGMS
Bjoern PetersLa Jolla Institute for ImmunologyDeveloping computational models to predict the immune response to B. pertussis booster vaccinationNIAID
David Claude RichardsonDuke UniversityExtending MolProbity Diagnosis & Healing Methods to Empower Better CryoEM & Xray Models at 2.5-4A Resolution, plus Versioned, Redeposited GEMS for Important Individual StructuresNIGMS
Pinaki SarderState University of New York at BuffaloComputational Imaging of Renal Structures for Diagnosing Diabetic NephropathyNIDDK
Michael R ShirtsUniversity of ColoradoOpen data-driven infrastructure for building biomolecular force fields for predictive biophysics and drug designNIGMS
Louis J SoslowskyUniversity of PennsylvaniaDifferential Roles of Collagen V in Establishing the Regional Properties in Mature and Aging Supraspinatus TendonsNIAMS
Andre Jan Willem van der KouweMassachusetts General HospitalNeuroimaging and gut microbiome markers of development in HIV-exposed uninfected infantsNICHD
Xiaoyin XuBrigham and Women's HospitalComputer aided diagnosis of cancer metastases in the brainNLM


This page last reviewed on April 6, 2023