NIH Awards 28 Supplements to Advance Software Tools for Open Science

Tuesday, December 29, 2020

In 2020 the National Institutes of Health (NIH) Office of Data Science Strategy (ODSS) and 24 institutes and centers (ICs) at NIH announced a notice for administrative supplements to enhance software tool development for open science (NOT-OD-20-073). Twenty-eight awards were made in the fall of 2020 to principal investigators at 26 different institutions across the United States.

These supplements will invest in research software tools with recognized value in a scientific community to enhance their impact by leveraging best practices in software development and advances in cloud computing. The supplements are intended to support collaborations between biomedical scientists and software engineers to enhance the design, implementation, and “cloud-readiness” of research software.

Through these awards, the NIH Office of Data Science Strategy and a trans-NIH team will help researchers who have developed scientifically valuable software to make tools sustainable, contribute to open science, and take advantage of new data science and computing paradigms.

Award Recipients
Principal Investigator	Institution	Project Title	NIH IC
Apkar Vania Apkarian	Northwestern University at Chicago	Brain Pathophysiology of Osteoarthritis Pain	NIAMS
Sylvain Bouix	Brigham and Women's Hospital	High Resolution, Comprehensive Atlases of the Human Brain Morphology	NIMH
Gregory R Bowman	Washington University	Allosteric impact of non-active-site mutations on enzymatic function	NIGMS
Laurel H. Carney	University of Rochester	Auditory Processing of Complex Sounds	NIDCD
Brian Yuan Chen	Lehigh University	Algorithmic identification of binding specificity mechanisms in proteins	NIGMS
Gerardo Andres Cisneros	University of North Texas	Investigation of DNA Modifying Enzymes by Computational Simulations: Development and Applications	NIGMS
Gaudenz Danuser	UT Southwestern Medical Center	Functional causality in regulating cell morphogenesis	NIGMS
Shireen Youssef Elhabian	University of Utah	Anatomy Directly from Imagery: General-purpose, Scalable, and Open-source Machine Learning Approaches	NIAMS
Melanie Fried-Oken	Oregon Health & Science University	Clinic Interactions of a Brain-Computer Interface for Communication	NIDCD
Ryan Gutenkunst	University of Arizona	Joint inferences of natural selection between sites and populations	NIGMS
John H.L. Hansen	University of Texas Dallas	CCI-Mobile: Signal Processing Advancements for Cochlear Implant Users in Naturalistic Environments	NIDCD
Carl Kesselman	University of Southern California	USC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration Hub	NIDCR
Steven H. Kleinstein	Yale University	Computational tools for the analysis of high-throughput immunoglobulin sequencing experiments	NIAID
Francine Laden	Harvard School of Public Health	Relationship Between Multiple Environmental Exposures and CVD Incidence and Survival: Vulnerability and Susceptibility	NIEHS
Suzanne Margaret Leal	Columbia University Health Sciences	Innovative approaches to elucidate the genetic etiology of age-related hearing impairment and tinnitus	NIDCD
Yaling Liu	Lehigh University	Multiscale Predictive Modeling of Blood Cell Damage with Experimental Verification	NHLBI
Shaun Aengus Mahony	Pennsylvania State University-University Park	Genome-wide structural organization of proteins within human gene regulatory complexes	NIGMS
Nadine Martin	Temple University of the Commonwealth	Translation and Clinical Implementation of a Test of Language and Short-term Memory (STM) in Aphasia	NIDCD
David P Miller	Wake Forest University Health Sciences	Effectiveness and Implementation of mPATH-CRC: A Mobile Health System for Colorectal Cancer Screening	NCI
David Lowell Mobley	University of California-Irvine	Advancing predictive physical modeling through focused development of model systems to drive new modeling innovations	NIGMS
Matteo Pellegrini	University of California Los Angeles	Enhancing the International Molecular Exchange (IMEx): Providing an Improved Community-Oriented Molecular Interactions Resource	NIGMS
Bjoern Peters	La Jolla Institute for Immunology	Developing computational models to predict the immune response to B. pertussis booster vaccination	NIAID
David Claude Richardson	Duke University	Extending MolProbity Diagnosis & Healing Methods to Empower Better CryoEM & Xray Models at 2.5-4A Resolution, plus Versioned, Redeposited GEMS for Important Individual Structures	NIGMS
Pinaki Sarder	State University of New York at Buffalo	Computational Imaging of Renal Structures for Diagnosing Diabetic Nephropathy	NIDDK
Michael R Shirts	University of Colorado	Open data-driven infrastructure for building biomolecular force fields for predictive biophysics and drug design	NIGMS
Louis J Soslowsky	University of Pennsylvania	Differential Roles of Collagen V in Establishing the Regional Properties in Mature and Aging Supraspinatus Tendons	NIAMS
Andre Jan Willem van der Kouwe	Massachusetts General Hospital	Neuroimaging and gut microbiome markers of development in HIV-exposed uninfected infants	NICHD
Xiaoyin Xu	Brigham and Women's Hospital	Computer aided diagnosis of cancer metastases in the brain	NLM